Chart 2 below illustrates the extent to which the reimbursement prices of the 15 States with the same estimated acquisition cost formula are dispersed throughout the price distribution of all 42 States. Each of the 42 States' unit prices for Dstrol a single source drug ; are arrayed from the lowest paying State to the highest. The unit prices of the States with an estimated acquisition cost of AWP minus 10 are indicated by a white square, and all other States' prices are indicated with a dark triangle. As shown, Pennsylvania has an estimated acquisition cost of AWP minus 10 percent and paid the sixth lowest unit price, while Nebraska has the same estimated acquisition cost, yet paid the highest price of the 42 States for this drug.e.
A codoxy cognex coke colazal capsules colazal rectal suspension colazal suppositories colazal tablets coldmist colfed-a colocort combantrin mebendazole combivent combivir comhist comhist la comprecin comvax concerta condylox congess congestac consupren contac cold capsules contuss cophene no 2 corax cordarone cordarone x cordilox corgonject cortate cortef cortenema corticotropin cortifoam cortisone acetate cortone cortone acetate cosopt cotrim cotrim ds cotrim pediatric covera hs coversyl coversyl plus crack crestor crinone crixivan crolon crolon capsules cromese cromese sterinebs cromolyn cromolyn capsules cromolyn sodium cromoptic cromoptic capsules cryocriptina cryopril cryosolona crysanal cryselle crystodigin curretab cyclan cyclandelate cyclessa cyclizine cyclobenzaprine cyclobenzaprine hydrochloride cyclopenthiazide cyclospasmol cyclosporin cyclosporine cycoflex cycrin cylert cymevene cyproheptadine hydrochloride cyprone cyprostat cyproterone acetate cysporin cytarabine cytarabine hydrochloride cytomel cytosar-u cytospaz cytotec cytovene dacarbazine daktagold dallergy-jr dalmane dantrium dantrolene dantrolene sodium dapa-tabs dapiprazole hydrochloride dapsone daraprim darvocet-n darvocet-n 100 darvocet-n 50 darvon darvon compound darvon compound-65 pulvules darvon pulvules darvon-n darvon-n compound darvon-n with asa dayto sulf decadron deconamine sr deconsal ii deconsal sprinkle defen la delavirdine delixir delta-d deltasone demadex demazin hot lemon demerol demulen 1 35 demulen 1 50 denavir denvar depacon depakene depakote depakote er depakote sprinkle depmedalone depo provera depo-medrol depo-ralovera depoject deponit depopred desogen desogestrel desyrel desyrel dividose detrol detrol la devrom devron deworm dexameth dexamethasone injection dexamphetamine dexaphen-sa dexbrompheniramine and pseudoephedrine dexchlorpheniramine dexchlorpheniramine maleate dexedrine dexmethsone dexone dextramphetamine sulfate dextroamphetamine sulfate dextropropoxyphene dextrostat dextrothyroxine sodium dhc plus di-spaz diamine t.
Your healthcare team may try different opioids and different doses of medication to find what works best for you. You may start with a low dose and increase the amount gradually to get the best pain relief. It may take a few weeks to adjust your medication to get the right opioid at the right dose to control your pain with the fewest side effects. Facts about opioid medications Addiction Many people with cancer fear that if they take opioids it will lead to addiction. Taking pain medication regularly for pain control is very different from addiction. Being addicted to a drug is complex, but a key part of it is psychological dependence on the drug. This happens when the need to continue using it becomes a craving or a compulsion that is more than just physical. Getting addicted to opioids is not likely to happen if you start out taking opioids to control pain. Your healthcare team will make sure that the medication you take regularly to help with your pain is just enough to keep your pain under control. Two effects of taking pain medication regularly are sometimes confused with addiction: Medicine tolerance: If you take opioids for pain, you may find that over time you need to take larger doses. This may be because your pain has increased, or it may be because you have developed a.
COMPETITION General. The pharmaceutical industry is characterized by rapidly evolving technology and intense competition. Many companies, including major pharmaceutical companies and specialized biotechnology companies, are engaged in marketing or development of products and therapies similar to those being pursued by us. Many of our competitors have substantially greater financial and other resources, larger research and development staffs and significantly greater experience in conducting clinical trials and other regulatory approval procedures, as well as in manufacturing and marketing pharmaceutical products, than we have. In the event we or our licensees market any products, we or they will compete with companies with well-established distribution networks and market position. Additional mergers and acquisitions in the pharmaceutical industry may result in even more resources being concentrated in our competitors. SANCTURA. Current therapy for OAB includes anticholinergics, such as Dwtrol and Dehrol LA tolterodine ; by Pfizer, Ditropan and Ditropan XL oxybutynin ; by Johnson & Johnson, Inc., Oxytrol oxybutynin transdermal patch ; by Watson Pharmaceuticals, Vesicare solifenacin ; by Astellas Pharma US, Inc. and Glaxo Smith Kline, Enablex darifenacin ; by Novartis A.G., and generic oxybutynin. Many of the products on the market for the treatment of OAB are available in once-a-day formulations, whereas SANCTURA is currently available as a twice-a-day formulation. Since launch, there have been over 300, 000 prescriptions written for SANCTURA representing approximately million of prescription value. NEBIDO. Current preferred methods for treating male hypogonadism are through-the-skin and injectable treatments. Through-the-skin treatments include gels, such as AndroGel by Solvay and Testim by Auxilium, and transdermal patch systems, such as AndroDerm by Watson. There are several additional gel products in development. There are multiple injectable products currently marketed in the U.S. which require more frequent injections than NEBIDO. Testosterone supplements are also available in oral dose forms, however, they are not widely prescribed for use in the United States. PRO 2000. Other than condoms, we are not aware of any product to prevent sexually-transmitted infections having been approved for use anywhere in the world. Approximately 60 new substances are being evaluated for this indication, but we believe only a few have reached the stage of development of PRO 2000. Advanced clinical stage topical microbicides include BufferGel by Reprotect, Inc., Savvy by Cellegy, Inc., Carraguard by The Population Council, and cellulose sulfate gel by Polydec Pharmaceuticals. IP 751. Current treatments for interstitial cystitis are aimed at relieving symptoms and include Elmiron pentosan polysulfate sodium ; , by Johnson & Johnson, and RIMSO 50 dimethyl sulfoxide ; , by Edwards Life Sciences Research. As a first line of defense against mild discomfort, physicians may recommend aspirin and ibuprofen. Some patients have experienced improvement by taking antidepressants or antihistamines. In patients with severe pain, narcotic analgesics or longer acting narcotics may be necessary. A variety of treatments are currently prescribed for pain and inflammatory disorders, including opioids, NSAIDs, COX-2 inhibitors and combinations of these drugs. The most prevalent types of pain are related to the back, post-operative recovery, osteoarthritis, diabetic neuropathy, rheumatoid arthritis and cancer. NSAIDs, the global leaders in pain treatment, include Celebrex celecoxib ; and Bextra valdecoxib ; by Pfizer. The principal marketed opioids include oxycontin and morphine. Pagoclone. According to the National Center for Stuttering, current treatment programs for this condition include speech therapies that are physical, psychological and nutritional, designed to reduce the tension on the vocal chords. We are not aware of any pharmaceutical products approved for the treatment of, or being developed for stuttering at this time. Aminocandin. There are several new echinocandins approved or under development for the treatment of esophageal candidiasis, invasive candidemia candidiasis, or aspergillosis. Cancidas caspofungin ; , by Merck & 15.
Patients with Alzheimer's disease being treated with cholinesterase inhibitors eg, tacrine [Cognex], donepezil [Aricept], rivastigmine tartrate [Exelon], galantamine HBr [Razadyne] ; , plus drugs with anticholinergic activity, had a greater decline in their mental status when tested after taking concurrent anticholinergic drugs for 2 years.2 It would seem obvious to avoid this combination. Two recent studies of patients taking cholinesterase inhibitors, however, found that anticholinergic drugs were coadministered in 33% to 35% of the patients.3, 4 While anticholinergic drugs may have been added to treat cholinesterase inhibitor side effects, this combination will likely result in reduced therapeutic efficacy of the cholinesterase inhibitor and perhaps the anticholinergic drug. Various cases have been noted of patients developing cognitive impairment when administered tolterodine tartrate Deyrol LA ; or oxybutynin chloride Ditropan XL.
Aciphex Actiq Actonel Actonel Actonel Actonel with Calcium Advair Diskus Advair HFA Aerobid M Albuterol Alupent Amerge Amerge Anzemet Anzemet Asmanex Atrovent ipratropium ; Atrovent ipratropium ; Atrovent HFA Axert Axert Azmacort Beconase AQ Boniva Boniva Celebrex Celebrex Cesamet Combivent Edtrol Detrol LA Ditropan oxybutynin ; 1mg, 2 mg 2 mg, 4 mg 5 mg 2.5 mg 150 mg 50 mg, 100 mg, 200 mg 400 mg 1 mg 6.25 mg 12.5 mg 0 .03% 0 .06% 2.5 mg 1 mg 50 mg 100 mg All strengths and diamox.
Read the Patient Information that comes with DETROL before you start using it and each time you get a refill. There may be new information. This leaflet does not take the place of talking with your doctor about your condition or your treatment. Only your doctor can determine if treatment with DETROL is right for you.
Medication costs and medical management costs are included. Medication costs are calculated using the average wholesale price AWP ; . The AWP for both drugs was obtained in December of 2004 from AnalySource, an online vendor of drug pricing data.17 The cost for tolterodine ER was based on Detrol LA 4 mg and was assumed to be and dulcolax.
Answer: raglan 2. Which of the following comes in a tablet and a liquid? a. Lotrisone b. Protonix c. Nexium d. Lomotil 3. Detrol is prescribed: a. Erectile dysfunction b. Gastroesophageal reflux disease c. Overactive bladder d. Glaucoma 4. Cimtetidine Which of the following is available as a syrup? a. Enablex b. Ditropan c. Detrol d. Chantix 5. An important counseling point with the antidiarrheal Lomotil is: a. Discontinue if clinical response is not seen within 48 hours b. Take early in the day to avoid insomnia c. Wash hands after touching d. Wait 5 minutes before inserting contact lens 6. What is the brand name for mupirocin?.
Are as complex as society and as individual as you or your child. Teens most frequently cite boredom as the cause. Easy access, low cost, and peer influence are other big factors. Historically, adolescents anxious for independence have always tried out exciting risky behavior, so it's not surprising youth experiment, particularly with readily accessible alcohol and marijuana. Fortunately, most experimenting teens don't move on to regular use and not all of those who use alcohol or drugs become dependent and ditropan.
The DUR Board has set a cumulativ e limit of 30 units 30 days for sedative-hypnotics effective 4 1 04. These include: Sonata, Halcion, Ambien, Prosom, Doral, Restoril and their generic equivalents. The DUR Board has set a a cumulative limit of 30units 30 days for Detrol LA and their generic LA equivalents effective 4 1 04. The DUR Board has placed Ditropan XL and Oxytrol and their generic equivalents on prior approval effective 4 1 04. Criteria requires docum ented failure on oral generic short acting oxybutynin chloride. The DUR Board has placed a prior approval on Olux clobetasol propionate ; foam and generic equivalents effective 4 1 04. Criteria requires documented failure on generic clobetasol propionates creams or ointments within the last 12 months. The DUR Board has placed a prior approval on Luxiq betamethasone valerate ; foam and generic equivalents effective 4 1 04. Criteria requires documented failure on generic betamethasone valerate creams or ointments within the last 12 months. G.
The committee recommends detrol and detrol la as a non-preferred agents that requires prior authorization and arava.
Seeman will screen transcripts from these genes in autopsied brains of patients with schizophrenia, depression, and controls in order to identify variants that are associated with schizophrenia. In addition, the prevalence of these variants will be determined in three brain regions implicated in schizophrenia--prefrontal cortex, striatum, and hippocampus. This work may lead to the identification of vulnerability genes for schizophrenia and to the development of new antipsychotic medications.
The Phase 2 and 3 clinical trial program for DETROL LA Capsules included 1073 patients who were treated with DETROL LA n 537 ; or placebo n 536 ; . The patients were treated with 2, 4, 6, or 8 mg day for up to 15 months. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The adverse reaction information from clinical trials does, however, provide a basis for identifying the adverse events that appear to be related to drug use and for approximating rates. The data described below reflect exposure to DETROL LA 4 mg once daily every morning in 505 patients and to placebo in 507 patients exposed for 12 weeks in the Phase 3, controlled clinical study and didronel.
Enablex darfenacin ; is a welcomed new medication for the treatment of overactive bladder, especially with the rise of reinforced cockpit doors and procedures. The FAA will allow this, as well as detrol in it's short acting form. Note that Ditropan or oxybutynin chloride is still not allowed by controllers or airmen. Chantix varenicline ; is a new medication recently approved by the FDA in May 2006. The FAA generally does not authorize new medications for use by ATCSs or pilots for at least one year after FDA approval. We recently confirmed that this is the case with Chantix. The FAA will not consider this medication for approval until at least the summer of 2007. Please see related information in the ATCS Sector section of this newsletter.
Hair, and she recalls her time in Mali with a certain wrv humor. The house she stayed in while in Sangui had been used as a shelter for sheep before she came and was turned into a pigsty after she left. A small brown snake lived in her latrine, and would curl up in a camouflaged coil on the seat she sat on while bathing. The villagers, she says, were of two minds: was it a deadly snake Kere literally, "My bite cannot be healed?-or a harmless mouse snake? It turned out to be the latter. ; Once, one of her neighbors and best friends in the tribe roasted her a rat as a special treat. "I told him that white people aren't allowed to eat rat because rat is our totem, " Strassmann says. "I can still see it. Bloated and charred. Stretched by its paws. Whiskers singed. To say nothing of the tail." Strassmann meant to live in Sangui for eighteen months, but her experiences there were so profound and exhilarating that she stayed for two and a half years. "I felt incredibly privileged, " she says. "I just couldn't tear myself away." Part of Strassmann's work focussed on the Dogon's practice of segregating menstruating women in special huts on and evista.
III. Read both of the following fact situations before responding to the questions. Situation I An employee with chronic schizophrenia, with the help of psychotropic medication to control his thought disorder, obtained a job in a warehouse loading boxes onto pallets for shipment. He does not come into contact with customers and has no regular contact with other employees. Over the course of the past several weeks he has come to work appearing increasingly disheveled. In addition, coworkers have complained that when they try to talk to him, even casually, he walks away or responds curtly. When he does talk, he is abrupt and rude. His work, however, remains satisfactory. The employer's handbook states that employees should have a neat appearance at all times and be courteous to other employees. When told that he is being disciplined for his appearance and his treatment of coworkers, the employee explains that his appearance and demeanor have deteriorated because of his mental condition that was exacerbated during this time period. Situation II.
VESICARE solifenacin succinate ; , Ditropan XL oxybutynin chloride ; , Oxytrol oxybutynin transdermal system ; , Detrol LA tolterodine tartrate ; and SancturaTM trospium chloride ; are anticholinergic agents indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency and urinary frequency. Vesicare has not been studied in comparative clinical trials with the other agents. Information in this response is based solely on the prescribing information for the individual products. All of these agents except for trospium are significantly metabolized by the cytochrome P450 enzyme system in the liver. Drugs that induce or inhibit this enzyme system have the potential to alter the pharmacokinetics of agents metabolized by the cytochrome P450 enzyme system. Active renal tubular secretion is a major route of elimination for trospium. Coadministration of trospium with drugs that are eliminated by active renal tubular secretion may increase the serum concentration of trospium and or the coadministered drug due to competition for this elimination pathway. Vesicare, Ditropan XL and Detrol LA may be administered once daily. The oxybutynin transdermal system is applied 3 to 4 times a week, and trospium is administered twice daily. The most common adverse events reported with these products are dry mouth, constipation and blurred vision and fosamax.
Abilify accolate actigall advicor bactrim beclomethasone bentyl benzamycin buspar caduet campral capozide cardene carmaz caverject cedax clonex dalmane ddavp demadex denavir depo-provera desquam-e detrol effexor eldepryl elocon epival esmolol evista factive felbatol femring flagyl flomax fluticasone gantrisin glucotrol guanabenz gyne lotrimin halcion helidac hydergine hytrin kaletra keppra kineret lac-hydrin lamictal lanoxin lescol levitra levsin lexapro macrodantin maxalt medrol meridia a drug is any biological substance, synthetic or non-synthetic, that is taken for non-dietary needs.
ENV JM MONO 2006 ; 29 9. REFFERENCES 1 ; Gimeno, S., Komen, H., Venderbosch, P.W.M., Bowmer, T. 1997 ; Disruption of sexual differentiation in genetic male common carp Cyprinus carpio ; exposed to an alkylphenol during different life stages. Environ. Sci. Technol. 31, 2884-2890. Jobling S, Sheahan D, Osborne JA, Matthiessen P, Sumpter JP. 1996. Inhibition of testicular growth in rainbow trout Oncorhynchus mykiss ; exposed to estrogenic alkylphenolic chemicals. Environ Toxicol Chem 15: 194202. Gray, M.A., Metcalfe, C.D. 1997 ; Induction of testis-ova in Japanese medaka Oryzias latipes ; exposed to p-nonylphenol. Environ. Toxicol. Chem. 16, 1082-1086. Kime DE, 1998. Endocrine Disruption in Fish. Kluwer Academi, Norwell, MA, USA. Parks LG, Cheek AO, Denslow ND, Heppell SA, McLachlan JA, LeBlanc GA, Sullivan CV. 1999. Fathead minnow Pimephales promelas ; vitellogenin: Purification, characterization, and quantitative immunoassay for the detection of estrogenic compounds. Comp Biochem Physiol 132C: 113-125. Tatarazako N, Koshio M, Hori H, Morita M and Iguchi T. 2004. Validation of an Enzyme-Linked Immunosorbent Assay Method for Vitellogenin in the Medaka. Journal of Health Science 50: 301-308. Holbech H, Andersen L, Petersen GI, Korsgaard B, Pedersen KL, Bjerregaard P, 2001. Development of an ELISA for vitellogenin in whole body homogenate of zebrafish Danio rerio ; . Comp Biochem Physiol C Toxicol Pharmacol.; 130 1 ; : 119-31. Nozaka T, Abe T, Matsuura T, Sakamoto T, Nakano N, Maeda M, Kobayashi K. 2004. Development of vitellogenin assay for endocrine disruptors using medaka Oryzias latipes ; . Environmental Sciences 11: 99-111. Ankley, G.T., K.M. Jensen, E.A. Makynen, M.D. Kahl, J.J. Korte, M.W. Hornung, T.R. Henry, J.S. Denny, R.L. Leino, V.S. Wilson, M.C. Cardon, P.C. Hartig and L.E. Gray. 2003. Effects of the androgenic growth promoter 17-B-trenbolone on fecundity and reproductive endocrinology of the fathead minnow Pimephales promelas ; . Environ. Toxicol. Chem. 22, 1350-1360 and rocaltrol.
Detrol dosing
TABLE 5. SUSCEPTIBILITY INTERPRETIVE CRITERIA FOR AZITHROMYCIN, SUSCEPTIBILITY TEST RESULT INTERPRETIVE CRITERIA!
The risk of early death is inversely related to fetal haemoglobin levels and
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Ims midas global sales audit, verispan longitudinal data, based on total prescriptions of detrol and detrol la for oab from april 1998 to december 2005.
Clinical Description Trichothecene mycotoxins might be weaponized and dis persed through the air or mixed in food or beverages. Initially, route-specific effects are typically prominent. Dermal expo sure leads to burning pain, redness, and blisters, and oral ex posure leads to vomiting and diarrhea. Ocular exposure might result in blurred vision, and inhalational exposure might cause nasal irritation and cough. Systemic symptoms can develop with all routes of exposure and might include weakness, ataxia, hypotension, coagulopathy, and death 128 ; . Laboratory Criteria for Diagnosis Biologic. Selected commercial laboratories are offering im munoassays to identify trichothecenes or trichothecene specific antibodies in human blood or urine 129130 ; . However, these procedures have not been analytically validated and are not recommended. Environmental. Detection of trichothecene mycotoxins in environmental samples, as determined by FDA. As a result of indoor air-quality investigations involving mold and potentially mold-related health effects, mycotoxin analy ses of bulk environmental samples are now commercially avail able through environmental microbiology laboratories in the and eulexin.
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TABLE 2. Toxicological background of the patients' consumption Total patients n Alcohol in g ; Opiates in ud ; Benzodiazepines in ud ; Cocaine in g ; Cannabis in ud ; Amphetamines in ud ; Hallucinogens in ud ; Inhalants Other substances Other addictive behaviors.
New data has recently been published regarding Detrol, the product marketed for overactive bladder. In the largest trial ever conducted for overactive bladder, Detrol two mg. twice a day showed a 54 percent improvement over placebo in reducing urge incontinence episodes. In this trial 1, 022 patients were included. Significantly, this patient group represented a "normal population" of patients with overactive bladder: 47 percent of the patients in this trial were treatment-nave, 32 percent had previously received some type of over active bladder treatment with a good effect and 21 percent had previously received some type of overactive bladder treatment with a poor effect. In stark contrast, Ditropan XL studies were only conducted with patients who had previously been treated and responded positively to Oxybutynin. In these studies with a biased patient population, Ditropan XL only showed an 84 percent improvement over placebo in the reduction of urge incontinence. There are no studies of Ditropan XL in a normal population. However, Oxybutynin has been studied in a normal population and in those studies, Oxybutynin showed a 60 percent improvement over placebo. It could be extrapolated that if you took those 84 percent of patient responders in the biased study population and multiplied that by the 60 percent of responders in the normal population, you would have a 51 percent improvement, which is similar to the improvement that is seen with Detrol. Are Detrol and Ditropan XL of equal efficacy? All head-to-head trials of Detrol versus Oxybutynin show equal efficacy, and although there are no head-to-head trials of Detrol versus Ditropan XL, equal efficacy can be assumed. Continued on next page.
I notice that when i'm on detrol i dizzy about an hour after taking the pill.
| Free DetrolIf you just look at the package inserts, for instance, comparing the ditropann xl package insert for [unintelligible], detrol la is 23%, 60% for ditropann xl, constipation, 6% detrol la, 13% for ditropann xl.
AtroPenAuto-Injector atropine injection ; U.S. package insert, King Pharmaceuticals, revised August 2004. Detrol LA tolterodine ; U.S. package insert, Pfizer, revised October 2005. 13 Gish P. Overview of AERS data for pediatric patients: tolterodine. DDRE ODS. DFS March 18, 2004. 14 Hirsch M. Medical Team Leader's Memo: Pediatric Efficacy Supplements NDA 20-897 SE8-009, NDA 17-577 SE8-033, NDA 18-211 SE8-016. DRUDP OND. DFS April 10, 2003. 17 and buy diamox.
Detrol Detrusitol tolterodine ; Detrol is an acetylcholine receptor antagonist indicated for incontinence and overactive bladder syndrome, for which it was first launched in 1997. Acetylcholine controls the parasympathetic nervous system which innervates the detrusor muscle. Antagonizing acetylcholine prevents acetylcholine from contracting the detrusor muscle and subsequently prevents inadvertent urination. The total number of people suffering from this disorder was estimated by Pharmacia to be 50 million worldwide and 15 million in the US. The current standard therapy for overactive bladder syndrome is SanofiSynthlabo and ALZA's Ditropan Ditropan XL oxybutynin ; , which has the same mechanism but in many patients causes dry mouth to a sufficient degree that many discontinue treatment after six months.
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325 5, 500 ml 5, 15, 30; ml; Consider generic equivalent. 20 ml 8 200 150, Consider generic alternatives. 225, 325, 425 ER Consider generic immediate release product, propafenone 2.25% neb OTC products are NOT covered. SC; IM Call 866-715-0874 for PA. Quantity Limit maximum - 34 days supply per fill 90 day fills not allowed ; 40% plaster Generic OTC is covered. 17% sol OTC products are NOT covered. 5, 7.5 Consider generic equivalent 17% gel OTC products are NOT covered. 500, 750 500, Non-Preferred brand. Preferred alternative s ; : oxybutynin, oxybutynin ext-rel, Detrol, and Detrol LA 60 ER 25, 50, 100; ml sol; IV.
Where X is a vector of firm characteristics. The year of the patent is the application year, most closely approximating the invention date. Publications and publications co-authored with university scientists are dated to the year of publication because that is the only date reliably available. The R&D expense to sales ratio, the log of the R&D expense, and the log of the number of employees are included with a lag of one year.30 Because there are many non-independent ; observations for each firm, I use clustered standard errors to account for correlation across observations for a given firm and provide robust White ; standard errors.31 The results of these estimations are reported in Table 5. All equations include year dummy variables to control for average time trends. The first equation includes only the R&D intensity.
While in theory these efforts should work to bring brokers' actions back into alignment with those of the lender investor, in practice they often fall short of the mark. As noted earlier, the broker has much more knowledge about the borrower's financial situation than the.
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